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Exercise “Reverses Cognitive Decline in Obese Mice”

Cognitive Decline

Story at-a-glance -

  • When obese mice exercised, they not only lost weight but also had reduced levels of interleukin-1 beta, an inflammatory cytokine
  • If left unchecked, interleukin-1 beta triggers a process that “eats up” neuronal synapses that are crucial for brain cells to communicate
  • As the levels of interleukin-1 beta dropped following exercise, the synaptic function in the mice was repaired, thereby reversing cognitive decline
  • Exercise boosts our brain health through multiple pathways, including jumpstarting neurogenesis, improving your hormone levels, increasing blood flow to your brain, reducing stress, and many others likely yet to be discovered

By Dr. Mercola

Obesity is associated with cognitive decline, at least in part because it results in an inflammatory state in your body. Obesity increases levels of inflammatory chemicals known as cytokines, which are strongly damaging to brain function.


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